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孙敬锋

2023年04月28日 16:34  点击:[]

一、个人简介

孙敬锋,男,汉族,理学博士,教授,硕士生导师。天津市水产学科“水产动物疾病及免疫学”研究方向带头人、天津农学院学术委员会委员、水产学院学术委员会主任,天津市高校学科领军人才培养计划和天津市“131”创新型人才第二层次人选。现兼任世界牡蛎学会会员、中国水产学会资深会员、天津农学院学报和Frontiers in Veterinary Science期刊编委、天津市海水养殖技术体系虾贝病害防控岗位专家。

二、研究方向

研究领域:水产养殖;渔业资源

研究方向:水产动物疾病及免疫学;渔业资源生物学

三、代表性科研成果

 

主持承担的主要科研项目  

 

1.国家自然科学基金面上项目,“膜联蛋白A2在海藻希瓦氏菌感染半滑舌鳎诱导肠道炎症中的作用及机理研究”,2020/01-2023/12。   

 

2.天津市海水养殖产业技术体系创新团队项目,“虾贝病害防控岗位”, 2021/01-2025/12。   

 

3.天津市自然科学基金重点项目,“半滑舌鳎膜联蛋白A2 在其肠道非特异性免疫应答中的功能研究”,2019/04-2022/03。   

 

4.天津市高校“学科领军人才培养计划”项目,“细菌性病原感染半滑舌鳎诱导肠道粘膜免疫应答的机制研究”,2018/09-2020/08。   

 

5.天津市企业科技特派员项目,“鱼类高效饲用复合益生菌的研制”,2018/10-2019/09。   

 

6.天津市水产产业技术体系项目,“养殖虾类和贝类病害生态防控岗位专家团队建设”,2017/01-2019/12。   

 

7.天津市北辰区科技创新专项项目,“海水养殖鱼类肠道益生菌筛选及应用研究”,50万元,2016/09-2018/08。   

 

8.天津市应用基础与前沿技术研究重点项目,“半滑舌鳎肠道菌群组成结构与机体免疫力相互关系的研究”,2015/04-2018/03。   

 

9.天津市“131”创新型人才培养工程第二层次人选资助计划项目,“虹鳟肠道菌群组成结构与机体免疫力相互关系的研究”,2012/10-2015/09。   

 

10.国家教育部科研重点项目,“牙鲆细胞因子MSH基因的克隆表达及免疫调节作用研究”,2009/01-2011/12,10万元。   

 

11.天津市应用基础与前沿技术研究一般项目,“鱼类一氧化氮合成酶免疫调控作用及机理研究”,2008/04-2011/03。   

 

12.中国博士后科学基金项目,“海洋贝类中类立克次体病原分子分类地位的鉴定”,2006/01-2007/05。   

 

13.广东省自然科学基金项目,“近江牡蛎类立克次体病原系统分类地位的鉴定”,2006/01-2007/12。   

 

14.天津市教委高等学校科技发展基金计划项目,“快速测定对虾非特异性免疫功能的流式细胞术方法研究”,2009/01-2011/12。   

 

15.天津农学院科研发展基金项目,“海水鱼类一氧化氮合成酶免疫调控研究”,2008/01-2010/12。   

 

授权发明专利:   

 

1.孙敬锋,韩卓然,吕爱军,石洪玥,胡秀彩. 一种提取鱼类肠道微生物基因组DNA的高温复合法. 专利号ZL201610086539.2。   

 

2.孙敬锋,毛晴,张峰. 一株鱼源屎肠球菌R8的筛选及应用. 专利号ZL201810499241.3。   

 

3.孙敬锋,韩卓然,毛晴,孙学亮. 促进鱼类肠道微生态恢复的饲料添加剂,制备方法及应用. 专利号ZL202110358918.3。   

 

4.孙敬锋,侯雨婷,毛晴,张燕玉,吕爱军,胡秀彩. 养殖鱼类病原海藻希瓦氏菌LAMP检测方法及应用. 专利号ZL201911260572.2。   

 

5.孙敬锋.改善肠道微生态结构的复合物,国际专利号LU502104。   

四、代表性论文

1.Xue Zhang, Jingfeng Sun*, Yonglong Zhu, Zhuoran Han, Xiucai Hu, Aijun Lv, Yongjun Guo. First record of isolation and characterization of Vibrio sinaloensis from diseased orange-spotted grouper Epinephelus coioides. Diseases of aquatic organisms, 2022,149: 71–76.

2.Zhongjie Zan, Zhuoran Han, Yuting Hou, Yanyu Zhang,Jingfeng Sun*. Development of a loop-mediated isothermal amplification method for detection of Shewanella algae in fish. Aquaculture Reports, 2022, 26:101292.

3.Xue Zhang, Jingfeng Sun*, Zhuoran Han, Feng Chen, Aijun Lv, Xiucai Hu, Xueliang Sun, Hongli Qi, Yongjun Guo. Vibrio parahaemolyticus alters the community composition and function of intestinal microbiota in Pacific white shrimp, Penaeus vannamei. Aquaculture. 2021, 544: 737061.

4.Xue Zhang, Jingfeng Sun*, Feng Chen, Hongli Qi, Limei Chen, Yeong Yik Sung, Yadong Huang, Aijun Lv, Xiucai Hu. Phenotypic and genomic characterization of a Vibrio parahaemolyticus strain causing diseases in Penaeus vannamei provides insights into its niche adaptation and pathogenic mechanism. Microbial genomics, 2021, 7:000549

5.Zhuoran Han, Jingfeng Sun*, Boyun Jiang, Xiucai Hu, Aijun Lv, Limei Chen, Yongjun Guo. Concurrent infections of Aeromonas veronii and Vibrio cholerae in koi carp (Cyprinus carpio var. koi). Aquaculture, 2021, 535: 111-122.

6.Zhuoran Han, Jingfeng Sun*, Xiufang Liu, Xueliang Sun, Hongyue Shi, Yongjun Guo. The delimitation of intestine segments of koi carp (Cyprinus carpio var. koi) based on histological features. Anatomia, Histologia, Embryologia, 2021, 50: 763-769.

7.Zhuoran Han, Jingfeng Sun*, Anli Wang, Aijun Lv, Xiucai Hu, Limei Chen, Yongjun Guo. Differentially expressed proteins in the intestine of Cynoglossus semilaevis Günther following a Shewanella algae challenge. Fish & Shellfish Immunology, 2020, 104:111-122.

8.Qing Mao, Xueliang Sun, Jingfeng Sun*, Feng Zhang, Aijun Lv, Xiucai Hu, Yongjun Guo. A candidate probiotic strain of Enterococcus faecium from the intestine of the crucian carp Carassius auratus. AMB Express, 2020, 10: 40.

9.Feng Chen, Jingfeng Sun*, Zhuoran Han, Xijun Yang, Jian-An Xian, Aijun Lv, Xiucai Hu, Hongyue Shi. Isolation, Identification and Characteristics of Aeromonas veronii From Diseased Crucian Carp (Carassius auratus gibelio). Frontiers in Microbiology, 2019, 10: 2742.

10.Boyun Jiang, Jingfeng Sun*, Aijun Lv, Xiucai Hu, Hongyue Shi, YeongYik Sung, Qingkui Wang, Yang Wang. Impact of DNA extraction methods on the observed microbial communities from the intestinal flora of the penaeid shrimp Litopenaeus vannamei. FEMS microbiology letters, 2019, 366 (9): 1-8.

11.Qing Mao, Zhuoran Han, Yinglan Li, Jingfeng Sun*, Yongjun Guo, Xueliang Sun, Limei Chen, Kezhi Xing. Histochemical distribution of three types of enzymes and mucous cells in the gill, mantle and hepatopancreas of the Ark shell Scapharca subcrenata. Journal of shellfish research, 2019, 38(2): 287-294.

12.Jingfeng Sun*, Yize Wang, Aijun Lv, Jian-an Xian, Qingkui Wang, Shulin Zhang, Yongjun Guo, Kezhi Xing. Histochemical distribution of four types of enzymes and mucous cells in the intestine of koi carp (Cyprinus carpio var. koi), Fish physiology and biochemistry, 2019, 45 (4): 1367-1376.

13.Jingfeng Sun*, Yongjun Guo*, Anli Wang, Aijun Lv, Xiucai Hu, Kezhi Xing. Flow cytometric analysis of the defense functions of hemocytes from the oyster, Crassostrea ariakensis. International journal of agriculture and biology, 2018, 20, 1413-1418.

14.Yize Wang, Jingfeng Sun*, Aijun Lv, Shunlin Zhang, Yeongyung Sung, Hongyue Shi, Xiucai Hu, Shuaijun Chen, Kezhi Xing. Histochemical distribution of four types of enzymes and mucous cells in the gastrointestinal tract of reared half-smooth tongue sole Cynoglossus semilaevis. Journal of fish biology, 2018, 92 (1): 3-16.

15.Zhuoran Han, Jingfeng Sun*, Aijun Lv, Jian-an Xian, Yeong Yik Sung Xueliang Sun, Xiucai Hu, Kezhi Xing. Transcriptome profiling of immune-responsive genes in the intestine of Cynoglossus semilaevis Günther challenged with Shewanella algae. Fish and shellfish immunology, 2018, 80, 291-301.

16.Zhuoran Han, Jingfeng Sun*, Aijun Lv, Wang Anli. Biases from different DNA extraction methods in intestine microbiome research based on 16S rDNA sequencing: a case in the koi carp, Cyprinus carpio var. Koi. MicrobiologyOpen, 2018, 8(1): e00626. DOI: 10.1002/MBO3.626.

17.Zhuoran Han, Jingfeng Sun*, Aijun Lv, Xueliang Sun, Hongyue Shi, Xiucai Hu, Qingkui Wang, Yongjun Guo, Kezhi Xing, Anli Wang. Changes in intestinal microflora of Cynoglossus semilaevis Günther following Shewanella algae infection. International journal of agriculture and biology, 2018, 20(4): 633-638.

18.Zhuoran Han, Jingfeng Sun*, Aijun Lv, YeongYik Sung, Xueliang Sun, Hongyue Shi, Xiucai Hu, Anli Wang, Kezhi Xing. A modified method for genomic DNA extraction from the fish intestinal microflora. AMB express, 2018, 8: 52.

19.Zhuoran Han, Jingfeng Sun*, Aijun Lv, YeongYik Sung, Hongyue Shi, Xiucai Hu, Kezhi Xing. Isolation, identification, and characterization of Shewanella algae from reared tongue sole, Cynoglossus semilaevis Günther. Aquaculture, 2017, 468, 356–362.

20.Jingfeng sun*, Anli wang, Jian-an xian, Aijun lv, Hongyue shi, Shulin zhang. Endoenzymes and mitochondrial membrane potential associated with hemocyte types in Macrobrachium rosenbergii. Journal of shellfish research, 2016, 35(2): 569–575.

21.Jingfeng Sun*, Anli Wang*, Tiejun Zhang. Flow cytometric analysis of defence functions of haemocytes from the penaeid shrimp, Penaeus vannamei. Journal of the world aquaculture society, 2010, 41, 93-105.

22.Jingfeng Sun*, Chengxun Chen, Anli Wang, Jian-an Xian. Flow cytometric analysis of effects of copper sulfate on hemocyte defence functions of the penaeid shrimp, Penaeus vannamei. Agricultural Reformation and Rural Progressing, 2010, 317-323.

23.Jingfeng Sun, Xinzhong Wu. Nitric oxide and superoxide anion generation in hemocytes of Crassostrea ariakensis stimulated with Rickettsia-like organisms and Zymosan. Journal of shellfish research, 2009, 28, 821-826.

24.Jingfeng Sun, Xinzhong Wu*, Weizhu Zhang. Morphological, structural, and functional characteristics of the haemocytes of the oyster, Crassostrea ariakensis. Journal of shellfish research, 2006, 25, 55-64.

25.Xinzhong Wu*#, Jingfeng Sun#, Weizhu Zhang, Bohai Wen. Purification and antigenic characteristics of the rickettsia-like organism from the oyster, Crassostrea ariakensis. Diseases of aquatic organisms, 2005, 67, 149-154.

26.Jingfeng Sun, Xinzhong Wu*. Histology, ultrastructure, and morphogenesis of a rickettsia- like organism causing diseases in the oyster, Crassostrea ariakensis Gould. Journal of Invertebrate Pathology, 2004, 86, 77-86.

27.Minghao Ye, Xiucai Hu, Aijun Lü*, Jingfeng Sun, Chengxun Chen. Isolation and genomic characterization of a pathogenic Providencia rettgeri strain G0519 in turtle Trachemys scripta. Antonie van Leeuwenhoek, 2020, 113: 1633-1662.

28.Jing Tan, Xiucai Hu, Aijun Lü*, Xiaoxue Liu, Jingfeng Sun, Yuchen Niu. Skin proteome profiling of tongue sole (Cynoglossus semilaevis) challenged with Vibrio vulnificus. Fish & Shellfish Immunology, 2020, 106: 1052-1066.

29.Jie Bai, Xiucai Hu, Aijun Lü*, Ruixia Wang, Rongrong Liu, Jingfeng Sun, Yuchen Niu. Skin transcriptome, tissue distribution of mucin genes and discovery of simple sequence repeats in Crucian carp Carassius auratus. Journal of Fish Biology, 2020, 97: 1542-1553.

30.Jing Liang, Xiucai Hu, Aijun Lü*, Jingfeng Sun. First report on the characterization of pathogenic Rahnella aquatilis KCL-5 from crucian carp: Revealed by genomic and proteomic analyses. Journal of Fish Diseases, 2020, 43(8): 1-26.

31.Jie Bai, Xiucai Hu, Ruixia Wang, Aijun Lü*, Jingfeng Sun. MicroRNA expression profile analysis of skin immune response in crucian carp (Carassius auratus) infected by Aeromonas hydrophila. Fish & Shellfish Immunology, 2020, 104: 673-785.

32.Zhengyi Lian, Jie Bai, Xiucai Hu, Aijun Lü*, Jingfeng Sun, Yongjun Guo, Yajiao Song. Detection and characterization of Aeromonas salmonicida subsp. salmonicida infection in crucian carp Carassius auratus. Veterinary Research Communications, 2020, 44(2): 61–72.

33.Rongrong Liu, Xiucai Hu, Aijun Lv, Yajiao Song, Zhengyi Lian, Jingfeng, Sun, et al. Proteomic profiling of zebrafish challenged by spring viremia of carp virus provides insight into skin antiviral response. Zebrafish, 2020, 17, 2: 91-103

34.Fuli Luo, Zhengyi Lian, Yuchen Niu, Aijun Lv, Jingfeng Sun. Molecular characterization of carp edema virus disease: an emerging threat to koi Cyprinus carpio in China. Microbial Pathogenesis, 2020, 149, 104551.

35.Yang Wang, Jingru Wang, Dongqing Bai, Yunlu Wei, Jingfeng Sun, Yunlong Luo, Jing Zhao, Ying Liu, Qingkui Wang. Synergistic inhibition mechanism of pediocin pa-1 and l-lactic acid against Aeromonas hydrophila. Biochimica et Biophysica Acta (BBA)-Biomembranes, 2020,1862(10), 183346.

36.Ruixia Wang, Xiucai Hu, Aijun Lü*, Rongrong Liu, Jingfeng Sun, Yeong Yik Sung, Yajiao Song. Transcriptome analysis in the skin of Carassius auratus challenged with Aeromonas hydrophila. Fish & Shellfish Immunology, 2019, 94:510-516.

37.Rongrong Liu, Zhengyi Lian, Xiucai Hu, Aijun Lü*, Jingfeng Sun, Chengxun Chen, Xiaoxue Liu, Yajiao Song, Yeong Yiksung. First report of Vibrio vulnificus infection in grass carp Ctenopharyngodon idellus in China. Aquaculture, 2018, 499:283-289.

38.Jian-an Xian*, Xiuxia Zhang, Jingfeng Sun, Lei Wang, Dongmei Wang, Juntao Li, Ruijun Duan, Yaopei Lu, Peihua Zheng. Flow cytometic analysis of Penaeus monodon, haemocyte responses to poly I: C. Fish and shellfish immunology, 2018, 74, 62-68.

39.Aijun Lü*, Ruixia Wang, Xiucai Hu, Jingfeng Sun, Li Li, Chao Pei, Chao Zhang, Guoxing Nie. First report of Rahnella aquatilis infection in crucian carp Carassius auratus in China. Diseases of Aquatic Organisms, 2017(123):205-212.

40.Aijun Lü*, Zhen Wei, Xiucai Hu, Jingfeng Sun, Chao Pei, Chao Zhang, Li Li, Ailing Li. Isolation and characterization of Acinetobacter lwoffii from the intestine of grass carp (Ctenopharyngodon idella). The Israeli Journal of Aquaculture-Bamidgeh, 2017, IJA_69.2017.1411

41.Yajiao Song, Xiucai Hu, Aijun Lü*, Jingfeng Sun, Yiksung Yeong, Chao Pei, Chao Zhang, Li Li. Isolation and characterization of Aeromonas veronii from ornamental fish species in China. The Israeli journal of aquaculture -Bamidgeh. 2017, IJA_69.2017.1446

42.Xiucai Hu, Xue Li, Aijun Lü*, Jingfeng Sun*, Hongyue Shi, Chengxun Chen, Li Li, Kong Xianghui. Isolation and characterization of Shewanella sp. Isolated from cultured loach Misgurnus anguillicaudatus. The Israeli Journal of Aquaculture-Bamidgeh, 2016,68(1294):1-9.

43.Aijun Lü*, Xiucai Hu, Li Li, Jingfeng Sun, Yajiao Song, Chao Pei, Chao Zhang, Kong Xianghui Kong. Isolation, identification, and antimicrobial susceptibility of pathogenic Aeromonas media isolated from diseased Koi carp (Cyprinus carpio koi). Iranian journal of fisheries sciences, 2016,15(2): 760-774.

44.Aijun Lü*, Yajiao Song, Xiucai Hu, Jingfeng Sun, Li Li., Chao Pei, Chao Zhang, Guoxing Nie. Aeromonas veronii, associated with skin ulcerative syndrome, isolated from the goldfish (Carassius auratus) in China. The Israeli Journal of Aquaculture-Bamidgeh, 2016,68(1321):1-10.

45.Aijun Lü*, Xiucai Hu, Li Li, Chao Pei, Chao Zhang, Xianglin Cao, Xianghui Kong, Guoxing Nie, Xuejun Li, Jingfeng Sun. Tissue distribution of olive flounder VDAC2 and its expression in fish cell lines. Fish Physiology Biochemistry, 2015, 41, 899–907.

46.Wenli Zhou, Hui Xiao, Xiuting Qiao, Jingfeng Sun, Kezhi Xing, Xuexi Tang. Quorum Sensing of an Associated Heterotrophic Bacteria-Z-QS01 with Chlorella Vulgaris and Response to Enhanced UV-B Radiation. Transaction of Beijing Institute of Technology 2011, 31(1):109-112

47.Chengxun Chen, Jingfeng Sun, Xiuting Qiao. Evaluation of efficacy about economically and ecologically to cultural system of Apostichopus japonicus through energy systemic model. Agricultural Reformation and Rural Progressing, 2010, 295-303. (ISTP)

48.Weizhu Zhang, Xinzhong Wu*, Jingfeng Sun, Dengfeng Li. Morphological and functional characterization of the haemocytes of the scallop, Chlamys farreri. Journal of shellfish research, 2005, 24, 931-936.

49.Jinhui Sun, Qingkui Wang*, Zhiyi Qiao, Dongqing Bai, Jingfeng Sun, Xiuting Qiao. Effect of LPS and outer membrane protein vaccines on immunological function and protection of grass carp (Ctenopharyngodon idella) against Aeromonas hydrophila. The Israeli journal of aquaculture Bamidgeh, 2012,64, 655-663.

50.Qing-Kui Wang, Cheng-Xun Chen, Yong-Jun Guo, Hai-Yun Zhao, Jing-Feng Sun, Shen Ma*, Ke-Zhi Xing. Dietary polysaccharide from Angelica sinensis enhanced cellular defence responses and disease resistance of grouper Epinephelus malabaricus. Aquaculture International, 2011,19, 945-956.

51.Mat Taib Mimi Iryani, Thomas H. MacRae, Patrick Sorgeloos, Tengku Sifzizul Tengku Muhammad, Muhd Danish-Daniel, Min Pau Tan, Woro Hastuti Satyantini, Mohd Effendy Abd Wahid, Jingfeng Sun, Aijun Lv, Yeong Yik Sung*. RNA interference of hsp70 in artemia Franciscana nauplii and its effect on morphology, growth, survival and immune response. Aquaculture, 2020, 520, 735012.

52.Kou Aishi, Saranya Sinnasamy, Thomas H. MacRae, Tengku Sifzizul Tengku Muhammad, Aijun Lv, Jingfeng Sun, Shuaijun Chen, Hongyue Shi, Tan Min Pau, Muhd Danish-Daniel Abdullah, Yeong Yik Sung*. Hsp70 knockdown reduced the tolerance of Litopenaeus vannamei post larvae to low pH and salinity. Aquaculture, 2019, 512, 734346.

Yeong Yik Sung, Nooridayu Abdul Rahman, Noor Azhar Mohamed Shazili, Shuaijun Chen, Aijun Lv, Jingfeng Sun, Hongyue Shi, Thomas H. MacRae. Non-lethal heat shock induces hsp70 synthesis and promotes tolerance against heat, ammonia and metals in post-larvae of the white leg shrimp Penaeus vannamei (boone, 1931). Aquaculture, 2018, 483, 21-26.

五、获奖情况

1.获天津市优秀本科毕业论文指导教师;连续多次并评为校级优秀本科和硕士研究生毕业论文指导教师。

2.“近江牡蛎类立克次氏体病及其防控关键技术与规模化应用” 项目成果获广西区科技进步二等奖。

六、联系方式

通讯地址:天津市西青区津静路22号天津农学院水产学院,邮编:300384。

电话:022-23781299;

邮箱:sun_jf@163.com

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